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Case Report
Three Cases of Pneumoperitoneum in Ventilated Newborns
Chun Ok Yang, Ho Young Lee, Won Kju Choe, Baek Keun Lim, Jong Soo Kim
Clin Exp Pediatr. 1995;38(7):1006-1011.   Published online July 15, 1995
Pneumoperitoneum in the newborn is usually a surgical emergency resulting from gastroint-estinal perforation. However, pneumoperitoneum can occur secondary to a pulmonary air leak which progresses from the mediastinum to the retroperitoneum by way of perivascular spaces and then to the peritoneum following rupture. We have observed this phenomenon in three ventilated newborn. A brief review of the related literatures was...
Original Article
Analysis of Contaminated Ground Water Inducing Methemoglobinemia and Epidemiologic Investigation of Contaminated Ground Water
Bu Heon Lee, Ji Young Suh, Nam Su Kim, Hang Lee, Young Yeul Kim, Bo Youl Choi, Hung Bae Park, Min Young Kim, In Hak Yeo
Clin Exp Pediatr. 1995;38(4):507-512.   Published online April 15, 1995
Purpose : Drining of Nitrate-contaminated water has been the most common cause of acquired methemoglobinemia. We had cyanotic infant diagnosed as methemoglobinemia caused by feeding with powdered formula mixed with nitrate-contaminated ground water. Methods : We had done epidemiologic investigation to identify the cause of an infant's methemoglobinemia. Analysis of ground water and blood test of involved family members and neighbors...
Case Report
Familial Erythrophagocytic Lymphohistiocytosis in Siblings
Eun Sook Lee, Ji Eun Choi, Dug Ha Kim, Hae Ran Lee, Chong Young Park
Clin Exp Pediatr. 1995;38(3):428-434.   Published online March 15, 1995
Familial erythrophagocytic lymphohistiocytosis(FEL) is an uncommon disorder characterized by multi-organ infiltration with phagocytic histiocytes and macrophages. It is a familial discorder presenting during infancy or young childhood with fever, hepartosplenomegaly, pancytopenia, bleeding diathesis, hypertriglyceridemia and neurologic manifestations. The course of the disease is extremely lethal and diagnosis of the disease during lifetime is very difficult. Exact diagnosis can only be...
Original Article
Infections in Children with Neoplastic Disease
Eun Hwa Choi, Jin Won Pyo, Jin Young Park, Kyung Bae Kwon, Bo Young Yun, Hee Young Shin, Hoan Jong Lee, Hyo Seop Ahn
Clin Exp Pediatr. 1995;38(3):366-377.   Published online March 15, 1995
Purpose : Infection is a major complication in patients with malignant disease. This study was performed to identify the causes and the etiologic agents of febrile infections and to characterize the clinical courses including the response to antimicrobial agents inpediatric cancer patients. Methods : This study reviewed 274 febrile episodes occurring in 163 children with neoplastic disease which were indentified prospectively...
Clinical Characteristics of Childhood Cerebrovascular Disease and Analysis on the Prognostic Factors
Yong Seung Hwang, Moon Sun Yang
Clin Exp Pediatr. 1995;38(3):353-365.   Published online March 15, 1995
Purpose : Cerebrovascular disease in children is more common than was once recognized and the etiology and prognosis of the disease in children are quite different from those of adults. Recently according to medical reports and clinical experiences, the incidence of childhood cerebrovascular disease is increasing in Korea. To clarify the clinical features of childhood cerebrovascular disease and to analyze its...
A Study on Clinical Characteristics of Maxillary Sinusitis in Korean Children
Dong Nam Kim, Sung Hee Oh, Hahng Lee
Clin Exp Pediatr. 1995;38(3):319-327.   Published online March 15, 1995
Purpose : Paranasal sinusitis, easily overlooked owing to it's benign symptomatology, should be considered when the upper respiratory tract infction persists longer than seven days. Without early recognition and appropriate management, the disease will take a chronic course and the incidence of complications will be increased. The significance of paranasal sinusitis among Korean children has not appropriately been appreciated; therefore,...
Case Report
Cystinuria 3 Cases
Ji Eun Choi, Bo Young Yun, Hae Won Park, Jae Hong Park, Il Sue Ha, Hae Il Jeong, Yong Choi, Hwang Choi, In Won Kim
Clin Exp Pediatr. 1995;38(2):245-251.   Published online February 15, 1995
We report three cases of cystinuria, presenting with urinary stones. A 2-year-old girl presented with urinary difficulty, hematuria, dysuria of sudden onset, and her 7-month-old younger brother also was presented with urinary difficulty, irritability on urination & stone passage. Other 6-month-old boy was admitted due to sudden onset anuria. They had radioopague renal & ureter stones and stone analysis revealed mixed...
Original Article
Acute Hemorrhagic Cystitis(AHC) in Children -Etiology and Clinical Characteristics-
Jin Won Pyo, Eun Hwa Choi, Jin Young Park, Hoan Jong Lee, Hae Il Cheong, Il Soo Ha, Yong Choi, Kwang Myung Kim, Hwang Choi, Je Geun Chi
Clin Exp Pediatr. 1995;38(2):207-215.   Published online February 15, 1995
Purpose : AHC characterized by sudden onset of gross hematuria, dysuria and frequency oc curs in children and young adults as a self-limited disease that should be differentiated from se rious renal disorders. We have performed this study to establish the cause and characterize the clinical features of this illness in Korean children. Methods : 19 cases collected prospectively for 30...
Cystic Kidney Disease According to Potter's Classification
Kee Hyuck Kim, Sung Chul Shin, Soon Il Lee, Je Geun Chi
Clin Exp Pediatr. 1995;38(1):91-98.   Published online January 15, 1995
The cystic disease of the kidney include a heterogeneous group of developmental, hereditary, and acquired disorders. Based on extensive microdissection studies, Potter concluded all renal cystic diseases could be categorized into four types. We have experienced 5 cases of cystic kidney disease which were confirmed by aoutopsy and classified as Type I, Type II, Type III, Boderline between types II and...
Observation of Social Background and Disease Patterns of Children in an Institute for Adoption (the 3rd report)
Jae Bong Kwon, Cheol Soon Park, Jae Wook Ko, Myung Ik Lee, Don Hee Ahn
Clin Exp Pediatr. 1995;38(1):81-90.   Published online January 15, 1995
Purpose : A Study was undertaken to assess the family background of abandonment and clinical and social aspects in an institute for foreign adoption. The results were compared to the previous two reports from the institute. Method : A sample of 1,728 children from 1987 to 1992 formed the subjects of the study by the medical records in the institution. Results :...
Recurrent Abdominal Pain in Children: Endoscopic Findings and Helicobacter pylori Infection
Cheol Ho Chang, Churl Young Chung
Clin Exp Pediatr. 1995;38(1):47-53.   Published online January 15, 1995
Purpose : Recurrent abdominal pain (RAP) in children is similar to nonulcer dyspepsia of adult. Recently, microscopic inflammation and Helicobacter pylori (H. pylori) infection have been suggested as possible causes of nonulcer dyspepsia in adults. The aim was to know the clinical significance of encoscopic findings and H. pylori infection in children with RAP. Methods : 128 children with RAP underwent...
Case Report
A Case of Remission of Systemic Juvenile Rheumatoid Arthritis (Still's Disease) Treated with High-dose Intravenous Gammaglobulin
Yon Sook Rho, Yun Woo Lee, Sang woo Kim
Clin Exp Pediatr. 1994;37(12):1767-1772.   Published online December 15, 1994
High dose intravenous gammaglobuline (IVIG) therapy is effective in some of the autoimmune diseases. Although the exact mechamism of action of IVIG is uncertain, the action as a neutralizing antibody against unknown etiologic agents, the action of blocking of Fc receptors of effector cells, or the action as a antiidiotypic antibody are suggested. We report a case of 12 year old...
A Case of Stillbirth Due to Fetomaternal Transfusion
Jin Min Choi, Myoung Bae Jeon, Byung Joo Park, Jung Hye Choi, Seoung Yul Lee, Dong Won Choi
Clin Exp Pediatr. 1994;37(12):1762-1766.   Published online December 15, 1994
Transfer of large quantities of fetal blood across the placental barrier to the maternal circulation is a rare occurrence which results in severe anemia in the newborn infants. This phenomenon is believed to occur most often during labor and delivery and apparently, is more frequent when abnormal obstetric conditions are present. However, fetal erythrocytes have been identified in the naternal...
Original Article
A Study on Prognostic Factors in Children with Encephalopathy
Jin Nyoung Park, In Joon Seol
Clin Exp Pediatr. 1994;37(12):1738-1745.   Published online December 15, 1994
To elucidate the clinical characteristics-especially its clinical pattern and outcome of chidren with encephalopathy, we carried out a retrospective review on medical records of 45 patients who were intially diagnosed as encephalopathy except mumps meningitis, Reye's syndome and neonatal hypoxic ischemic encephalopathy at the Department of pediatrics, Hanyang University children's hospital from January 1986 to February 1994. The results were summerized...
Diagnosis of Thoracic Lesions in Children by Fine Needle Aspiration Biopsy
Dong Nam Kim, Nam Su Kim, Hahng Lee, Jong Sung Kim, Suk Chul Jeon
Clin Exp Pediatr. 1994;37(11):1559-1564.   Published online November 15, 1994
To elucidate the clinical availability of FNAB, we reviewed retrospectively medical records of 30 patients who had infiltrative pulmonary lesion or pulmonary nodule of mediastinal mass, and got percutaneous fine needle aspiration biopsy using Wescott needle, 20~22 gauge, at the department of Pediatrics, Hanyang university hospital from July, 1986 to June, 1993. The obtained results were as follow: 1) There were 30...
Antilymphocyte Globulin Therapy for Aplastic Anemia in Children
Soo Jong Hong, Hee Young Shin, Hyo Seop Ahn
Clin Exp Pediatr. 1994;37(11):1526-1539.   Published online November 15, 1994
Immunosuppressive therapy based on the use of antilymphocyte globulin (ALG) has become standard therapy for patients with aplastic anemia who are not eligible for bone marrow transplantation. In this study, T cell subsets before and after ALG therapy, hematologic responses, complications and prognostic factors were analysed. Eleven (42%) out of twenty-six patients treated with ALG showed response, but...
Case Report
A Case of Congenital T Cell Lymphoblastic Lymphoma
Eun Sun Yoo, Young Mi Hong, Kyung Hee Kim, Hae Soo Gyu, Eun Chul Chung
Clin Exp Pediatr. 1994;37(9):1296-1304.   Published online September 15, 1994
T cell lymphoblastic lymphoma is characterized by immature lymphoid cells that are indistinguishable from the lymphoblasts and prolymphocytes of acute lymphoblastic leukemia. Several characteristic clinical features of lymphoblastic lymphoma, with include a high male-to-female ratio, a relatively high incidence in older children and young adults, the frequent presence of mediastinal involvement at the time of diagnosis. Also, this disease is...
Familial Hemophagocytic Lymphohistiocytosis
Dong Un Kim, Dae Kyun Koh, Yeon Dong Lee, Jae Kyun Hur, Kyoo Hong Cho, Suk Jin Kang
Clin Exp Pediatr. 1994;37(9):1279-1285.   Published online September 15, 1994
Familial hemophagocytic lymphohistiocytosis (FHL) is a rare disease characterized by fever, hepatosplenomegaly, cytopenia and non-malignant lymphohistiocytic infiltration with hemophagocytosis in reticuloendothelial organs. We experienced three cases of FHL in identical male twins and their younger brother who presented with fever and severe hepatosplenomegaly. Cytompenia, elevated serum transaminase and low serum albumin levels, hypertriglyceridemia were common laboratory findings of them. One of...
One Case of Maffucco's Syndrome with Testicular Teratoma
Seung Mo Park, Duk Hi Kim, Ho Seong Kim
Clin Exp Pediatr. 1994;37(8):1162-1168.   Published online August 15, 1994
Maffucci's syndrome is a very rare, congenital and non-hereditary mesodermal dysplasia manifested by multiple enchondromas and soft tissue hemangiomas. Since Maffucci had reported this syndrome in 1881, there have been more than 100 cases reported, and also there has been reported that Maffuddi's syndrome has various interstitial tumor. However there hasn't been any report about Maffucci's syndrome with testicular teratoma....
A Case of Pulmonary Blastoma
Yun Jeong Chang, Jeong Hee Kim, Sun Ki Kim, Byong Kwan Son, Joon Mi Kim, Young Chae Chu
Clin Exp Pediatr. 1994;37(7):999-1005.   Published online July 15, 1994
Pulmonary blastoma is a rare type of malignant lung tumor comprised of epithelial and mesenchymal elements reminiscent of fetal lung. Mesenchymal element may show various patterns of differentiation toward mature tissue, such as cartilage, smooth muscle, and bone. Rhabdomyoblastic differentiation in pulmonary blastoma is quite rare. Our case of pulmonary blastoma with rhabdomyoblastic differentiation documented by electron microscopy and immunohistochemistry. Usually...
Original Article
Protective Effect of Breast Feeding for Infection
Jin Kyung Jung, In Nam Kang, Dong Ju Sin, Doo Bong Lee
Clin Exp Pediatr. 1994;37(7):906-912.   Published online July 15, 1994
A Comparative study was retrospectively performed with 374 infants in order to find protective effect of breast feeding for infection. This study shows that breast feeding protect infant against gastrointestinal and respiratory infcttion. Breast feeding offers advantage by reducting gastraintestinal and respiratory infection when they should maintain breast feeding for at least three months. 1) First year morbidity increased with extent of artificial...
Occult Mediastinal Ganglioneuroblastoma Presenting with Myoclonic Encephalopathy as Paraneoplastic Syndrome
Hahng Lee, Dong Ki Han, Jae Won Oh, In Joon Seol, Eun Kyung Hong, Seok Chol Jeon
Clin Exp Pediatr. 1994;37(5):695-700.   Published online May 15, 1994
Ganglioneruroblastoma and neuroblastoma are among commonest types of childhood malignancy and a number of unique paraneoplastic syndromes have been associated with both localized and disseminated neuroblastoma. The coincidence of neuroblastoma and myoclonic encephalopathy or other paraneoplastic syndromes occurs relatively rare, and therefore, failure to recognize this association could result in delays in both diagnosis and treatment, and the result...
The Effect of Cranial Irradiation on Growth of Children with Lymphatic Origin Tumors
Jin Seoup Jung, Yon Sook Rho, Sang Woo Kim
Clin Exp Pediatr. 1994;37(5):666-671.   Published online May 15, 1994
A retrospective study was conducted to investigate the effects of CNS prophylaxis with 1,800cGy cranial irradiation on standing height growth of children with acute lymphoblastic leukemia(ALL). Seventeen longterm survivors (DFS over 5 years) of ALL and Non-Hodgkins Lymphoma who had been admitted at pediatric department of Inje University Seoul Paik Hospital from January 1982 to September 1988 were studied. The long term...
Primary Cutaneous Aspergillosis in Leukemic Children
Jin Young Park, Mee Ran Kim, Hee Young Shin, Hoan Jong Lee, Hyo Seop Ahn, Je Guen Chi
Clin Exp Pediatr. 1994;37(4):520-526.   Published online April 15, 1994
Primary cutaneous aspergillosis is rare. In this report we describe primary skin infection by Aspergillus in 9 children with leukemia. The skin lesion was characterized clinically by erythematous macule and papule associated with pain and itching, followed by a rapid progression to ulcer and central black eschars with raised erythematous border at the site of venipuncture, insertion of intravenous cannula,...
Mechanism of Impaired Growth Hormone Response in Children with Simple Obesity
Moon Sung Park, Mi Jung Park, Ho Seong Kim, Duk Hi Kim
Clin Exp Pediatr. 1994;37(4):457-463.   Published online April 15, 1994
Obesity is associated with an impairment of the hormone secretion elicited by all stimuli known to date, but the basic mechanism of this alteration is unknown, To determine whether obesity is associated with a chronic state of tonic somatostatin, several tests with growth hormone stimuli such as GHRH (1㎍/kg), clonidine (150㎍/m2) and Resular insulin (0.1U/kg, subcutaneously), to obese subjects and...
Case Report
Two Case of Psedohypoaldosteronism Type 1
Ji Eun Lee, Jung Wan Seo, Seung Joo Lee
Clin Exp Pediatr. 1994;37(1):122-128.   Published online January 15, 1994
Pseudohypoaldosteronism type 1 is a genetic renal tubular disease of salt wasting, presenting in young infants. Tubular unresponsiveness to elevated endogenous an exogenou aldosterone is the suggested pathogenetic mechanism. Oral sodium chloride supplementation relieve the clinical symptoms and electrolyte distrubances. We experienced 2 cases of PHA type 1 in 38-day and 450day old male infants who were presented with failure to...
Original Article
Diagnostic Significance of Red Cell Indices in Non-anemic Iron Deficiency and Iron Deficiency Anemia: Reevaluation with ROC Curve
Hwang Min Kim, Won Kyu Choi, Jae Seung Yang, Jong Soo Kim
Clin Exp Pediatr. 1994;37(1):33-39.   Published online January 15, 1994
To validate the diagnostic significance of red cell indices in non-anemic iron deficiency and iron deficiency anemia, complete blood count, serum iron, total iron binding capacity, and serum ferritin were measured in 208 middle school girls between 13 and 15 years age. We used Reciever Operating Characteristic (ROC) curve to compare the diagnostic significances of various red cell indices (MCV,...
Case Report
A Case of Sacrococcygeal Teratoma with Spina Bifida Cystica in Newborn
Tae Woo Kim, Sung Ki Park, Young Soo Baik, Hee Sin Ko, Dong Uk Kim, Woo Taek Kim, Woong Hm Kim, Chang Yeun Lee, Young Bae Lee
Clin Exp Pediatr. 1993;36(12):1747-1751.   Published online December 15, 1993
Sacrococcygeal teratoma is a rare tumor, it occurs once in every 40,000 live births. Most of the reported cases appear in female infant (M:F=1:4). They deserve clinical attention because they are potenially malignant and are curable if diagnosed and treated early. The patients may have associated congenital anomalies. This patient has spina bifida cystica in lower sacrum. Brief review of related literature is included...
Original Article
Chronic Idiopathic Intestinal pseudo-obstrucion Syndrome in Childhood
Jae Geon Sim, Jeong Kee Seo, Kui Won Park, Je Geun Chi
Clin Exp Pediatr. 1993;36(11):1583-1595.   Published online November 15, 1993
Chronic idiopathic intestinal pseudo-obstruction syndrome is a clinical condition induced by an impaired function of intestinal motility. Although its clinical symptoms are those of intestinal obstruction, mechanical obstruction of the intestine cannot be found by vigorous studies, even by operative exploration. We have experienced nine cases of chronic idiopathic intestinal pseudo-obstruction syndrome. It will help in diagnosis and treatment of the...
A Clinical Study of Histiocytosis Syndrome
Hye Yong Lee, Chul Hee Chung, Won Suk Suh, Sang Mann Shin, Sang Jhoo Lee
Clin Exp Pediatr. 1993;36(10):1417-1425.   Published online October 15, 1993
We made a clinical study on 10 cases of histiocytosis syndrome who had been admitted to the pediatric department of Soon Chun Hyang University Hospital from Jan 1982 to Dec. 1991. The results were obtained as follows 1) The sex incidence revealed male predominance with the ratio 4:1. 2) Among 10 cases, 4 cases were classified as eosinophilic granuloma, 1 case as Letterer-Siwe...
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